Dr. Veena S. Patil
Human immunology, Infectious diseases, Non-coding RNAs, Genomics
We are a lab of human immunology, interested in understanding the overall immune response to infections. Our main focus is to understand the development of immune response by studying the regulation of global gene expression patterns uniquely associated with a pathogen, immune cell-type and/ disease stage using multi-omics and immunological tools. Two major research activities in the lab are:
1. T cell memory development to infectious diseases
The acquisition of immunological memory to infections is a hallmark of protective immunity and hence forms the basis for vaccinations. During this evolutionarily conserved process of T cell immunological memory development, the naive T cells that have not previously encountered antigen, differentiate during the primary infection into memory T cells that have specialized functions in immune defence to a later infection with the same pathogen. Each pathogen elicits a specialized memory subset and once formed this specialized T cell memory can provide life-long immunity to the same pathogen. My lab is mainly i
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